Pharmacological evaluation of some synthesized thiazolidinone derivatives containing Mannich base of sydnone and p-phenylenediamine
By: Savant, Suchitra S
.
Contributor(s): Vashi, Parikshit I.
Publisher: New Delhi CSIR 2022Edition: Vol.61(6), Jun.Description: 591-598p.Subject(s): GENERAL CHEMISTRYOnline resources: Click here
In:
Indian journal of chemistry (Section B)Summary: A series of 4-thiazolidinone derivatives incorporating Mannich base of 3-(3-nitrophenyl)sydnone have been synthesized by conventional routes and evaluated for their antimicrobial activities against E. coli, P. aerugenosa, S. aureus, S. pyogenus, C. albicans, A. niger and A. clavatus. Most of the compounds show moderate to very good biological activity. The structures of synthesized compounds 7a-j have been elucidated by C, H, and N analysis, FT-IR, 1H and 13C NMR and mass spectrometry.
| Item type | Current location | Call number | Status | Date due | Barcode | Item holds |
|---|---|---|---|---|---|---|
Articles Abstract Database
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School of Pharmacy Archieval Section | Not for loan | 2023-0747 |
Total holds: 0
A series of 4-thiazolidinone derivatives incorporating Mannich base of 3-(3-nitrophenyl)sydnone have been synthesized by conventional routes and evaluated for their antimicrobial activities against E. coli, P. aerugenosa, S. aureus, S. pyogenus, C. albicans, A. niger and A. clavatus. Most of the compounds show moderate to very good biological activity. The structures of synthesized compounds 7a-j have been elucidated by C, H, and N analysis, FT-IR, 1H and 13C NMR and mass spectrometry.
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